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Women's unique risk factors


Heart disease and stroke is the leading cause of death for Canadian women, and yet many are not aware of this threat.

In fact, most Canadian women have at least one risk factor for heart disease and stroke. Women who have diabetes, come from certain ethnic backgrounds or are menopausal are even more at risk.
It is important for every woman to know about their risk factors and recognize the signs for heart disease and stroke so that you can prevent and manage them.

Women tend to be safeguarded from heart disease prior to menopause because of the protective effect of estrogen.  However, this is not always the case. For example, pre-menopausal women with diabetes have similar risk to men of the same age because diabetes cancels out the protective effect of estrogen.

The role of Estrogen

During a woman's reproductive life cycle, from about age 12 to 50, the naturally occurring hormone, estrogen, provides a protective effect on women's heart health. However, estrogen's protective effect can change depending on a variety of factors and conditions.  

Birth control pills (oral contraceptives)

Modern oral contraceptives are much safer than the forms used decades ago. In women under the age of 35 who don't smoke, contraceptive use does not increase the risk of stroke. However, in a small proportion of women, oral contraceptives increase the risk of high blood pressure and blood clots. The risk is greater if you: smoke, already have high blood pressure, are over the age of 40, have other risk factors for heart disease or stroke, or already have a blood clotting problem.

Pregnancy

Over the nine months of gestation, women may develop certain conditions that put them at higher risk of heart disease and stroke.

  • Pre-eclampsia is a condition that typically starts after the 20th week of pregnancy. It is related to increased blood pressure and protein in the mother's urine (the protein indicates that there is a problem with the kidneys). Although there is no proven way to prevent pre-eclampsia, you may be prone to the condition if you have high blood pressure or are obese prior to becoming pregnant. Other risk factors include being younger than 20 or older than 40, are pregnant with more than one baby, or have diabetes, kidney disease, rheumatoid arthritis, lupus or scleroderma. All women should be monitored by their healthcare provider throughout their pregnancy. Have your blood pressure checked often. Pre-eclampsia is treatable under the supervision of a doctor.
  • Gestational diabetes While pregnant, a woman's body must produce extra insulin because increasing levels of pregnancy hormones interfere with the body's ability to use insulin efficiently. If the woman's body can't produce the additional insulin sufficiently, her blood sugar levels may rise, causing gestational diabetes. There are no warning signs so it is important that women have their glucose levels monitored as part of their prenatal care and continue to be monitored throughout their pregnancy. Gestational diabetes can increase the risk of the mother and baby developing diabetes later in life. Diabetes is a risk factor for heart disease and stroke.
  • The risk of a pregnancy-related stroke can happen at any stage of pregnancy.   A high risk time is during childbirth and the first few months after birth. It is usually the result of an underlying problem such as a pre-existing blood vessel malformation or eclampsia. Read about the signs of stroke.
Menopause

Menopause is a time when a woman stops having menstrual cycles. If you have reached menopause, your overall risk of heart disease may increase due to the reduction in the hormones estrogen and progesterone produced by your body. Before and after menopause, you may experience:

  • An increase in total blood cholesterol, low density lipoprotein cholesterol (LDL or ‘bad’ cholesterol) and triglyceride levels
  • A decrease in high density lipoprotein cholesterol (HDL or ‘good’ cholesterol)
  • A tendency toward higher blood pressure
  • An increase in central body fat, which can be harmful to your body because you may be more prone to  blood clots and blood sugar problems Symptoms such as severe sweating or sleep disturbances

Hormone Replacement Therapy:

Women who are taking estrogen as part of Hormone Replacement Therapy (HRT) have an increased risk of stroke and heart attack. If you are on HRT, discuss with a healthcare professional what this means for you and what your options are.

Cholesterol

You may have heard or read that natural estrogen helps to keep cholesterol levels in a healthy range. After menopause, as natural estrogen levels drop, more and more women tend to develop high cholesterol. Talk with your doctor about how often you should have your cholesterol checked. Read How to Manage Your Cholesterol.

Triglycerides

Triglycerides are the most common type of fat in the body. A high triglyceride level often goes with higher levels of total cholesterol and LDL, lower levels of HDL and an increased risk of diabetes. Research suggests that having high triglycerides may increase the risk of heart disease and stroke for women. Talk to your doctor about your risk.

Making Heart-Healthy Changes in your life

A woman’s overall risk of heart disease or stroke is determined by all of her risk factors. You can control some of these risk factors, but not all of them.

Risk factors that you can control include smoking, high blood pressure, high blood cholesterol, diabetes, physical inactivity and obesity.

Risk factors that you cannot control include age, gender, family history and ethnicity.

Women can prevent and reduce their risk of heart disease by:

  • Becoming and remaining smoke free.
  • Achieving and maintaining a healthy body weight.
  • Being physically active for at least 150 minutes of moderate- to vigorous-intensity aerobic physical activity per week, in bouts of 10 minutes or more. Maintaining a blood pressure through lifestyle changes (such as increased physical activity) and when needed through medication.
  • Eating a healthy diet that is lower in fat, higher in fibre and includes foods from each of the four food groups in Canada’s Food Guide.
  • Using medications to reduce the risk of heart disease and stroke as prescribed by your healthcare provider, for example medications for high blood pressure, high blood cholesterol and diabetes, or other medications like acetylsalicylic acid (ASA commonly known as AspirinTM)

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